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Category :   Buy and Sell / Fashion and Beauty
Price :    299/-
Product Type:    New - 
Title :    Buy hydrocodone
Discription :    

Hydrocodone is a semi-synthetic opioid medication that is classified as a Schedule II drug. This medication is approved by the U.S. Food and Drug Administration (FDA) and used for pain management.

 

Hydrocodone is primarily used to treat severe chronic pain that requires opioid analgesia and is not effectively treated by nonopioid alternatives. Hydrocodone is used in combination formulations to treat nonproductive cough in adults and has antitussive properties. Hydrocodone functions as an opioid receptor agonist and activates mu-opioid receptors to produce analgesic effects. In addition, hydrocodone activates delta- and kappa-opioid receptors as the plasma drug concentration increases beyond the starting doses.

 

This activity focuses on single-ingredient hydrocodone for pain relief. This activity outlines the indications, mechanism of action, significant adverse effects, contraindications, monitoring, toxicity, and other critical elements of hydrocodone therapy in the clinical setting. These details are essential for the interprofessional healthcare teams responsible for managing the care of patients with pain and related conditions and sequelae.

 

 

Adverse Effects

The most common adverse effects of hydrocodone include frequent constipation and nausea. Additional adverse effects of hydrocodone include the following:

  • Respiratory: Severe respiratory depression, shortness of breath, respiratory tract infection 

  • Cardiovascular: Hypotension, bradycardia, and peripheral edema 

  • Neurologic: Headache, chills, anxiety, sedation, insomnia, dizziness, drowsiness, and fatigue 

  • Dermatologic: Pruritus, diaphoresis, and rash

  • Gastrointestinal: Vomiting, dyspepsia, gastroenteritis, constipation, and abdominal pain Genitourinary: Urinary tract infection and urinary retention associated with prostatic hypertrophy 

  • Otic: Tinnitus and sensorineural hearing loss (SNHL)

  • Endocrine: Secondary adrenal insufficiency

Drug-Drug Interactions

  • Concurrent use of hydrocodone with central nervous system depressants, such as alcohol, benzodiazepines, barbiturates, or other opioids, can result in profound sedation and respiratory depression; therefore, these combinations must be avoided.

  • Medications that induce (eg, rifampin, phenytoin, and carbamazepine) or inhibit (eg, cimetidine, fluoxetine, and ritonavir) cytochrome enzymes should be closely monitored. This can re

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